Neuropediatrics, Table of Contents Neuropediatrics 1995; 26(2): 126-127DOI: 10.1055/s-2007-979742 Neurobiology and neuroimaging © Hippokrates Verlag GmbH StuttgartCerebral Proton Magnetic Resonance Spectroscopy in Rett SyndromeF. Hanefeld1 , H.-J. Christen1 , U. Holzbach1 , B. Kruse1 , J. Frahm2 , W. Hänicke2 1Kinderklinik, Schwerpunkt Neuropädiatrie, Georg-August-Universität, Robert-Koch-Str. 40, Göttingen 2Biomedizinische NMR-Forschungs GmbH, Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany Recommend Article Abstract PDF Download Buy Article Abstract Combined MRI/MRS studies were performed in 9 girls with Rett syndrome of different ages. NAA, as marker of neuronal tissue, was found to decrease with increasing age. There was no evidence for a defective energy metabolism. The data point towards a probably secondary degenerative process in the pathogenesis of Rett syndrome. Key words Rett syndrome - MR spectroscopy PDF (241 kb)
